2013 classification criteria for systemic sclerosis: an American college of rheumatology/European league against rheumatism collaborative initiative
Identifieur interne : 000410 ( France/Analysis ); précédent : 000409; suivant : 0004112013 classification criteria for systemic sclerosis: an American college of rheumatology/European league against rheumatism collaborative initiative
Auteurs : Frank Van Den Hoogen [Pays-Bas] ; Dinesh Khanna [États-Unis] ; Jaap Fransen [Pays-Bas] ; Sindhu R. Johnson [Canada] ; Murray Baron [Canada] ; Alan Tyndall [Suisse] ; Marco Matucci-Cerinic [Italie] ; Raymond P. Naden [Nouvelle-Zélande] ; Thomas A. Medsger [États-Unis] ; Patricia E. Carreira [Espagne] ; Gabriela Riemekasten [Allemagne] ; Philip J. Clements [États-Unis] ; Christopher P. Denton [Royaume-Uni] ; Oliver Distler [Suisse] ; Yannick Allanore [France] ; Daniel E. Furst [États-Unis] ; Armando Gabrielli [Italie] ; Maureen D. Mayes [États-Unis] ; Jacob M. Van Laar [Royaume-Uni] ; James R. Seibold [États-Unis] ; Laszlo Czirjak [Hongrie] ; Virginia D. Steen [États-Unis] ; Murat Inanc [Turquie] ; Otylia Kowal-Bielecka [Pologne] ; Ulf Müller-Ladner [Allemagne] ; Gabriele Valentini [Italie] ; Douglas J. Veale [Irlande (pays)] ; Madelon C. Vonk [Pays-Bas] ; Ulrich A. Walker [Suisse] ; Lorinda Chung [États-Unis] ; David H. Collier [États-Unis] ; Mary Ellen Csuka [États-Unis] ; Barri J. Fessler [Royaume-Uni] ; Serena Guiducci [Italie] ; Ariane Herrick [Royaume-Uni] ; Vivien M. Hsu [États-Unis] ; Sergio Jimenez [États-Unis] ; Bashar Kahaleh [États-Unis] ; Peter A. Merkel [États-Unis] ; Stanislav Sierakowski [Pologne] ; Richard M. Silver [États-Unis] ; Robert W. Simms [États-Unis] ; John Varga [États-Unis] ; Janet E. Pope [Canada]Source :
- Annals of the Rheumatic Diseases [ 0003-4967 ] ; 2013-11.
English descriptors
- KwdEn :
- Abnormal nailfold capillaries, Actelion, American college, American rheumatism association, Anticentromere, Anticentromere antibody, Antinuclear antibody testing, Arterial hypertension, Arthritis, Arthritis care, Arthritis rheum, Autoantibody, Bursal friction rubs, Candidate criteria, Candidate items, Capillaroscopy, Classification criteria, Clin, Clinical experts, Connective tissue disease, Consecutive patients, Consensus methods, Consulting fees, Criteria development, Criteria sets, Criteria table, Criterion, Derivation cohort, Derivation sample, Diabetic cheiroarthropathy, Disease duration, Disease manifestations, Draft system, Eosinophilic fasciitis, European league, Exion contractures, Expert consensus, Expert opinion, Generalised morphea, Health care london, Heart catheterisation, Higher score, Honorarium, Hoogen, Hypertension, Initial threshold, Interstitial lung disease, Iterative changes, Leroy, Lichen sclerosis, Limited cutaneous, Lung disease, Maximum score, Medical university, Medsger, Metacarpophalangeal, Metacarpophalangeal joints, Multicriteria decision analysis, Nailfold, Nailfold capillaries, Nailfold capillaroscopy, Nailfold capillary pattern, Nailfold visualisation, Ngers, Ngertip lesions, Patient data, Physician diagnosis, Point system, Preliminary criteria, Present work, Prospective study, Proximal, Proximal interphalangeal, Pulmonary artery hypertension, Radboud university nijmegen, Random sample, Renal crisis, Research grants, Rheum, Rheumatic disease, Rheumatic diseases, Rheumatism, Rheumatism criteria, Rheumatoid arthritis, Rheumatol, Rheumatology, Scleredema diabeticorum, Scleroderma, Scleroderma criteria, Sclerosis, Systemic, Systemic lupus erythematosus, Systemic sclerosis, Systemic sclerosis criteria, Telangiectasia, Tissue disease, Total score, Validation, Validation cohort, Validation sample, Weighted, Whole finger, Years time.
- Teeft :
- Abnormal nailfold capillaries, Actelion, American college, American rheumatism association, Anticentromere, Anticentromere antibody, Antinuclear antibody testing, Arterial hypertension, Arthritis, Arthritis care, Arthritis rheum, Autoantibody, Bursal friction rubs, Candidate criteria, Candidate items, Capillaroscopy, Classification criteria, Clin, Clinical experts, Connective tissue disease, Consecutive patients, Consensus methods, Consulting fees, Criteria development, Criteria sets, Criteria table, Criterion, Derivation cohort, Derivation sample, Diabetic cheiroarthropathy, Disease duration, Disease manifestations, Draft system, Eosinophilic fasciitis, European league, Exion contractures, Expert consensus, Expert opinion, Generalised morphea, Health care london, Heart catheterisation, Higher score, Honorarium, Hoogen, Hypertension, Initial threshold, Interstitial lung disease, Iterative changes, Leroy, Lichen sclerosis, Limited cutaneous, Lung disease, Maximum score, Medical university, Medsger, Metacarpophalangeal, Metacarpophalangeal joints, Multicriteria decision analysis, Nailfold, Nailfold capillaries, Nailfold capillaroscopy, Nailfold capillary pattern, Nailfold visualisation, Ngers, Ngertip lesions, Patient data, Physician diagnosis, Point system, Preliminary criteria, Present work, Prospective study, Proximal, Proximal interphalangeal, Pulmonary artery hypertension, Radboud university nijmegen, Random sample, Renal crisis, Research grants, Rheum, Rheumatic disease, Rheumatic diseases, Rheumatism, Rheumatism criteria, Rheumatoid arthritis, Rheumatol, Rheumatology, Scleredema diabeticorum, Scleroderma, Scleroderma criteria, Sclerosis, Systemic, Systemic lupus erythematosus, Systemic sclerosis, Systemic sclerosis criteria, Telangiectasia, Tissue disease, Total score, Validation, Validation cohort, Validation sample, Weighted, Whole finger, Years time.
Abstract
Objective The 1980 American College of Rheumatology (ACR) classification criteria for systemic sclerosis (SSc) lack sensitivity for early SSc and limited cutaneous SSc. The present work, by a joint committee of the ACR and the European League Against Rheumatism (EULAR), was undertaken for the purpose of developing new classification criteria for SSc. Methods Using consensus methods, 23 candidate items were arranged in a multicriteria additive point system with a threshold to classify cases as SSc. The classification system was reduced by clustering items and simplifying weights. The system was tested by (1) determining specificity and sensitivity in SSc cases and controls with scleroderma-like disorders, and (2) validating against the combined view of a group of experts on a set of cases with or without SSc. Results It was determined that skin thickening of the fingers extending proximal to the metacarpophalangeal joints is sufficient for the patient to be classified as having SSc; if that is not present, seven additive items apply, with varying weights for each: skin thickening of the fingers, fingertip lesions, telangiectasia, abnormal nailfold capillaries, interstitial lung disease or pulmonary arterial hypertension, Raynaud's phenomenon, and SSc-related autoantibodies. Sensitivity and specificity in the validation sample were, respectively, 0.91 and 0.92 for the new classification criteria and 0.75 and 0.72 for the 1980 ACR classification criteria. All selected cases were classified in accordance with consensus-based expert opinion. All cases classified as SSc according to the 1980 ACR criteria were classified as SSc with the new criteria, and several additional cases were now considered to be SSc. Conclusions The ACR/EULAR classification criteria for SSc performed better than the 1980 ACR criteria for SSc and should allow for more patients to be classified correctly as having the disease.
Url:
DOI: 10.1136/annrheumdis-2013-204424
Affiliations:
- Allemagne, Canada, Espagne, France, Hongrie, Irlande (pays), Italie, Nouvelle-Zélande, Pays-Bas, Pologne, Royaume-Uni, Suisse, Turquie, États-Unis
- Angleterre, Berlin, Californie, Caroline du Sud, Colorado, Communauté de Madrid, Connecticut, District de Columbia, Grand Londres, Grand Manchester, Gueldre, Illinois, Massachusetts, Michigan, Midlands de l'Ouest, New Jersey, Ohio, Ontario, Pennsylvanie, Texas, Île-de-France
- Berlin, Birmingham, Londres, Los Angeles, Madrid, Manchester, Nimègue, Paris, Toronto
- Université de Manchester, Université de Toronto
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Johnson</name><affiliation wicri:level="4"><country xml:lang="fr">Canada</country><wicri:regionArea>Toronto Western Hospital, Mount Sinai Hospital, and University of Toronto, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Baron, Murray" sort="Baron, Murray" uniqKey="Baron M" first="Murray" last="Baron">Murray Baron</name><affiliation wicri:level="1"><country xml:lang="fr">Canada</country><wicri:regionArea>Jewish General Hospital and McGill University, Montreal, Quebec</wicri:regionArea><wicri:noRegion>Quebec</wicri:noRegion></affiliation></author><author><name sortKey="Tyndall, Alan" sort="Tyndall, Alan" uniqKey="Tyndall A" first="Alan" last="Tyndall">Alan Tyndall</name><affiliation wicri:level="1"><country xml:lang="fr">Suisse</country><wicri:regionArea>Felix Platter Spital and University of Basel, Basel</wicri:regionArea><wicri:noRegion>Basel</wicri:noRegion></affiliation></author><author><name sortKey="Matucci Cerinic, Marco" sort="Matucci Cerinic, Marco" uniqKey="Matucci Cerinic M" first="Marco" last="Matucci-Cerinic">Marco Matucci-Cerinic</name><affiliation wicri:level="1"><country xml:lang="fr">Italie</country><wicri:regionArea>University of Florence, Florence</wicri:regionArea><wicri:noRegion>Florence</wicri:noRegion></affiliation></author><author><name sortKey="Naden, Raymond P" sort="Naden, Raymond P" uniqKey="Naden R" first="Raymond P" last="Naden">Raymond P. Naden</name><affiliation wicri:level="1"><country xml:lang="fr">Nouvelle-Zélande</country><wicri:regionArea>Auckland City Hospital and New Zealand Health Ministry, Auckland</wicri:regionArea><wicri:noRegion>Auckland</wicri:noRegion></affiliation></author><author><name sortKey="Medsger, Thomas A" sort="Medsger, Thomas A" uniqKey="Medsger T" first="Thomas A" last="Medsger">Thomas A. Medsger</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Carreira, Patricia E" sort="Carreira, Patricia E" uniqKey="Carreira P" first="Patricia E" last="Carreira">Patricia E. Carreira</name><affiliation wicri:level="3"><country xml:lang="fr">Espagne</country><wicri:regionArea>Hospital Universitario 12 de Octubre, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Riemekasten, Gabriela" sort="Riemekasten, Gabriela" uniqKey="Riemekasten G" first="Gabriela" last="Riemekasten">Gabriela Riemekasten</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Charité University Medicine Berlin, German Rheumatology Research Center, and Leibniz Institute, Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Clements, Philip J" sort="Clements, Philip J" uniqKey="Clements P" first="Philip J" last="Clements">Philip J. Clements</name><affiliation wicri:level="3"><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of California, Los Angeles, David Geffen School of Medicine, Los Angeles</wicri:regionArea><placeName><settlement type="city">Los Angeles</settlement><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Denton, Christopher P" sort="Denton, Christopher P" uniqKey="Denton C" first="Christopher P" last="Denton">Christopher P. Denton</name><affiliation wicri:level="3"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Royal Free Hospital and University College London Medical School, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Distler, Oliver" sort="Distler, Oliver" uniqKey="Distler O" first="Oliver" last="Distler">Oliver Distler</name><affiliation wicri:level="1"><country xml:lang="fr">Suisse</country><wicri:regionArea>University Hospital Zurich, Zurich</wicri:regionArea><wicri:noRegion>Zurich</wicri:noRegion></affiliation></author><author><name sortKey="Allanore, Yannick" sort="Allanore, Yannick" uniqKey="Allanore Y" first="Yannick" last="Allanore">Yannick Allanore</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Université Paris Descartes and Hôpital Cochin, AP-HP, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Furst, Daniel E" sort="Furst, Daniel E" uniqKey="Furst D" first="Daniel E" last="Furst">Daniel E. Furst</name><affiliation wicri:level="3"><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of California, Los Angeles, David Geffen School of Medicine, Los Angeles</wicri:regionArea><placeName><settlement type="city">Los Angeles</settlement><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Gabrielli, Armando" sort="Gabrielli, Armando" uniqKey="Gabrielli A" first="Armando" last="Gabrielli">Armando Gabrielli</name><affiliation wicri:level="1"><country xml:lang="fr">Italie</country><wicri:regionArea>Clinica Medica Università Politecnica delle Marche, Ancona</wicri:regionArea><wicri:noRegion>Ancona</wicri:noRegion></affiliation></author><author><name sortKey="Mayes, Maureen D" sort="Mayes, Maureen D" uniqKey="Mayes M" first="Maureen D" last="Mayes">Maureen D. Mayes</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Texas Health Science Center, Houston, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Van Laar, Jacob M" sort="Van Laar, Jacob M" uniqKey="Van Laar J" first="Jacob M" last="Van Laar">Jacob M. Van Laar</name><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Newcastle University Medical School, Newcastle upon Tyne</wicri:regionArea><wicri:noRegion>Newcastle upon Tyne</wicri:noRegion></affiliation></author><author><name sortKey="Seibold, James R" sort="Seibold, James R" uniqKey="Seibold J" first="James R" last="Seibold">James R. Seibold</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Scleroderma Research Consultants, Avon, Connecticut</wicri:regionArea><placeName><region type="state">Connecticut</region></placeName></affiliation></author><author><name sortKey="Czirjak, Laszlo" sort="Czirjak, Laszlo" uniqKey="Czirjak L" first="Laszlo" last="Czirjak">Laszlo Czirjak</name><affiliation wicri:level="1"><country xml:lang="fr">Hongrie</country><wicri:regionArea>University of Pécs Medical Center, Pécs</wicri:regionArea><wicri:noRegion>Pécs</wicri:noRegion></affiliation></author><author><name sortKey="Steen, Virginia D" sort="Steen, Virginia D" uniqKey="Steen V" first="Virginia D" last="Steen">Virginia D. Steen</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Georgetown University School of Medicine, Washington, DC</wicri:regionArea><placeName><region type="state">District de Columbia</region></placeName></affiliation></author><author><name sortKey="Inanc, Murat" sort="Inanc, Murat" uniqKey="Inanc M" first="Murat" last="Inanc">Murat Inanc</name><affiliation wicri:level="1"><country xml:lang="fr">Turquie</country><wicri:regionArea>Istanbul University, Istanbul</wicri:regionArea><wicri:noRegion>Istanbul</wicri:noRegion></affiliation></author><author><name sortKey="Kowal Bielecka, Otylia" sort="Kowal Bielecka, Otylia" uniqKey="Kowal Bielecka O" first="Otylia" last="Kowal-Bielecka">Otylia Kowal-Bielecka</name><affiliation wicri:level="1"><country xml:lang="fr">Pologne</country><wicri:regionArea>Medical University of Bialystok, Bialystok</wicri:regionArea><wicri:noRegion>Bialystok</wicri:noRegion></affiliation></author><author><name sortKey="Muller Ladner, Ulf" sort="Muller Ladner, Ulf" uniqKey="Muller Ladner U" first="Ulf" last="Müller-Ladner">Ulf Müller-Ladner</name><affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Justus-Liebig University Giessen and Kerckhoff Clinic, Bad Nauheim</wicri:regionArea><wicri:noRegion>Bad Nauheim</wicri:noRegion><wicri:noRegion>Bad Nauheim</wicri:noRegion></affiliation></author><author><name sortKey="Valentini, Gabriele" sort="Valentini, Gabriele" uniqKey="Valentini G" first="Gabriele" last="Valentini">Gabriele Valentini</name><affiliation wicri:level="1"><country xml:lang="fr">Italie</country><wicri:regionArea>Second University of Naples, Naples</wicri:regionArea><wicri:noRegion>Naples</wicri:noRegion></affiliation></author><author><name sortKey="Veale, Douglas J" sort="Veale, Douglas J" uniqKey="Veale D" first="Douglas J" last="Veale">Douglas J. Veale</name><affiliation wicri:level="1"><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>St. Vincent's University Hospital, Dublin</wicri:regionArea><wicri:noRegion>Dublin</wicri:noRegion></affiliation></author><author><name sortKey="Vonk, Madelon C" sort="Vonk, Madelon C" uniqKey="Vonk M" first="Madelon C" last="Vonk">Madelon C. Vonk</name><affiliation wicri:level="3"><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Radboud University Nijmegen Medical Centre, Nijmegen</wicri:regionArea><placeName><settlement type="city">Nimègue</settlement><region type="province" nuts="2">Gueldre</region></placeName></affiliation></author><author><name sortKey="Walker, Ulrich A" sort="Walker, Ulrich A" uniqKey="Walker U" first="Ulrich A" last="Walker">Ulrich A. Walker</name><affiliation wicri:level="1"><country xml:lang="fr">Suisse</country><wicri:regionArea>Felix Platter Spital and University of Basel, Basel</wicri:regionArea><wicri:noRegion>Basel</wicri:noRegion></affiliation></author><author><name sortKey="Chung, Lorinda" sort="Chung, Lorinda" uniqKey="Chung L" first="Lorinda" last="Chung">Lorinda Chung</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Stanford University School of Medicine, Stanford, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Collier, David H" sort="Collier, David H" uniqKey="Collier D" first="David H" last="Collier">David H. Collier</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Colorado Medical School and Denver Health Medical Center, Denver, Colorado</wicri:regionArea><placeName><region type="state">Colorado</region></placeName></affiliation><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Amgen, Thousand Oaks, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Ellen Csuka, Mary" sort="Ellen Csuka, Mary" uniqKey="Ellen Csuka M" first="Mary" last="Ellen Csuka">Mary Ellen Csuka</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Medical College of Wisconsin, Milwaukee, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Fessler, Barri J" sort="Fessler, Barri J" uniqKey="Fessler B" first="Barri J" last="Fessler">Barri J. Fessler</name><affiliation wicri:level="3"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>University of Alabama at Birmingham, Birmingham</wicri:regionArea><placeName><settlement type="city">Birmingham</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Midlands de l'Ouest</region></placeName></affiliation></author><author><name sortKey="Guiducci, Serena" sort="Guiducci, Serena" uniqKey="Guiducci S" first="Serena" last="Guiducci">Serena Guiducci</name><affiliation wicri:level="1"><country xml:lang="fr">Italie</country><wicri:regionArea>University of Florence, Florence</wicri:regionArea><wicri:noRegion>Florence</wicri:noRegion></affiliation></author><author><name sortKey="Herrick, Ariane" sort="Herrick, Ariane" uniqKey="Herrick A" first="Ariane" last="Herrick">Ariane Herrick</name><affiliation wicri:level="4"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>University of Manchester, Manchester</wicri:regionArea><placeName><settlement type="city">Manchester</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Manchester</region><settlement type="city">Manchester</settlement></placeName><orgName type="university">Université de Manchester</orgName></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Salford Royal National Health Service Foundation Trust, Salford</wicri:regionArea><wicri:noRegion>Salford</wicri:noRegion></affiliation></author><author><name sortKey="Hsu, Vivien M" sort="Hsu, Vivien M" uniqKey="Hsu V" first="Vivien M" last="Hsu">Vivien M. Hsu</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Jimenez, Sergio" sort="Jimenez, Sergio" uniqKey="Jimenez S" first="Sergio" last="Jimenez">Sergio Jimenez</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Thomas Jefferson University, Philadelphia, Pennsylvania</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Kahaleh, Bashar" sort="Kahaleh, Bashar" uniqKey="Kahaleh B" first="Bashar" last="Kahaleh">Bashar Kahaleh</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Toledo, Toledo, Ohio</wicri:regionArea><placeName><region type="state">Ohio</region></placeName></affiliation></author><author><name sortKey="Merkel, Peter A" sort="Merkel, Peter A" uniqKey="Merkel P" first="Peter A" last="Merkel">Peter A. Merkel</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Pennsylvania, Philadelphia, Pennsylvania</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Boston University School of Medicine, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Sierakowski, Stanislav" sort="Sierakowski, Stanislav" uniqKey="Sierakowski S" first="Stanislav" last="Sierakowski">Stanislav Sierakowski</name><affiliation wicri:level="1"><country xml:lang="fr">Pologne</country><wicri:regionArea>Medical University of Bialystok, Bialystok</wicri:regionArea><wicri:noRegion>Bialystok</wicri:noRegion></affiliation></author><author><name sortKey="Silver, Richard M" sort="Silver, Richard M" uniqKey="Silver R" first="Richard M" last="Silver">Richard M. Silver</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Medical University of South Carolina, Charleston, South Carolina</wicri:regionArea><placeName><region type="state">Caroline du Sud</region></placeName></affiliation></author><author><name sortKey="Simms, Robert W" sort="Simms, Robert W" uniqKey="Simms R" first="Robert W" last="Simms">Robert W. Simms</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Boston University School of Medicine, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Varga, John" sort="Varga, John" uniqKey="Varga J" first="John" last="Varga">John Varga</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Northwestern University Feinberg School of Medicine, Chicago, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Pope, Janet E" sort="Pope, Janet E" uniqKey="Pope J" first="Janet E" last="Pope">Janet E. Pope</name><affiliation wicri:level="1"><country xml:lang="fr">Canada</country><wicri:regionArea>St. Joseph's Health Care London and University of Western Ontario, London, Ontario</wicri:regionArea><wicri:noRegion>Ontario</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j">Annals of the Rheumatic Diseases</title><title level="j" type="abbrev">Ann Rheum Dis</title><idno type="ISSN">0003-4967</idno><idno type="eISSN">1468-2060</idno><imprint><publisher>BMJ Publishing Group Ltd and European League Against Rheumatism</publisher><date type="published" when="2013-11">2013-11</date><biblScope unit="volume">72</biblScope><biblScope unit="issue">11</biblScope><biblScope unit="page" from="1747">1747</biblScope></imprint><idno type="ISSN">0003-4967</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0003-4967</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Abnormal nailfold capillaries</term><term>Actelion</term><term>American college</term><term>American rheumatism association</term><term>Anticentromere</term><term>Anticentromere antibody</term><term>Antinuclear antibody testing</term><term>Arterial hypertension</term><term>Arthritis</term><term>Arthritis care</term><term>Arthritis rheum</term><term>Autoantibody</term><term>Bursal friction rubs</term><term>Candidate criteria</term><term>Candidate items</term><term>Capillaroscopy</term><term>Classification criteria</term><term>Clin</term><term>Clinical experts</term><term>Connective tissue disease</term><term>Consecutive patients</term><term>Consensus methods</term><term>Consulting fees</term><term>Criteria development</term><term>Criteria sets</term><term>Criteria table</term><term>Criterion</term><term>Derivation cohort</term><term>Derivation sample</term><term>Diabetic cheiroarthropathy</term><term>Disease duration</term><term>Disease manifestations</term><term>Draft system</term><term>Eosinophilic fasciitis</term><term>European league</term><term>Exion contractures</term><term>Expert consensus</term><term>Expert opinion</term><term>Generalised morphea</term><term>Health care london</term><term>Heart catheterisation</term><term>Higher score</term><term>Honorarium</term><term>Hoogen</term><term>Hypertension</term><term>Initial threshold</term><term>Interstitial lung disease</term><term>Iterative changes</term><term>Leroy</term><term>Lichen sclerosis</term><term>Limited cutaneous</term><term>Lung disease</term><term>Maximum score</term><term>Medical university</term><term>Medsger</term><term>Metacarpophalangeal</term><term>Metacarpophalangeal joints</term><term>Multicriteria decision analysis</term><term>Nailfold</term><term>Nailfold capillaries</term><term>Nailfold capillaroscopy</term><term>Nailfold capillary pattern</term><term>Nailfold visualisation</term><term>Ngers</term><term>Ngertip lesions</term><term>Patient data</term><term>Physician diagnosis</term><term>Point system</term><term>Preliminary criteria</term><term>Present work</term><term>Prospective study</term><term>Proximal</term><term>Proximal interphalangeal</term><term>Pulmonary artery hypertension</term><term>Radboud university nijmegen</term><term>Random sample</term><term>Renal crisis</term><term>Research grants</term><term>Rheum</term><term>Rheumatic disease</term><term>Rheumatic diseases</term><term>Rheumatism</term><term>Rheumatism criteria</term><term>Rheumatoid arthritis</term><term>Rheumatol</term><term>Rheumatology</term><term>Scleredema diabeticorum</term><term>Scleroderma</term><term>Scleroderma criteria</term><term>Sclerosis</term><term>Systemic</term><term>Systemic lupus erythematosus</term><term>Systemic sclerosis</term><term>Systemic sclerosis criteria</term><term>Telangiectasia</term><term>Tissue disease</term><term>Total score</term><term>Validation</term><term>Validation cohort</term><term>Validation sample</term><term>Weighted</term><term>Whole finger</term><term>Years time</term></keywords><keywords scheme="Teeft" xml:lang="en"><term>Abnormal nailfold capillaries</term><term>Actelion</term><term>American college</term><term>American rheumatism association</term><term>Anticentromere</term><term>Anticentromere antibody</term><term>Antinuclear antibody testing</term><term>Arterial hypertension</term><term>Arthritis</term><term>Arthritis care</term><term>Arthritis rheum</term><term>Autoantibody</term><term>Bursal friction rubs</term><term>Candidate criteria</term><term>Candidate items</term><term>Capillaroscopy</term><term>Classification criteria</term><term>Clin</term><term>Clinical experts</term><term>Connective tissue disease</term><term>Consecutive patients</term><term>Consensus methods</term><term>Consulting fees</term><term>Criteria development</term><term>Criteria sets</term><term>Criteria table</term><term>Criterion</term><term>Derivation cohort</term><term>Derivation sample</term><term>Diabetic cheiroarthropathy</term><term>Disease duration</term><term>Disease manifestations</term><term>Draft system</term><term>Eosinophilic fasciitis</term><term>European league</term><term>Exion contractures</term><term>Expert consensus</term><term>Expert opinion</term><term>Generalised morphea</term><term>Health care london</term><term>Heart catheterisation</term><term>Higher score</term><term>Honorarium</term><term>Hoogen</term><term>Hypertension</term><term>Initial threshold</term><term>Interstitial lung disease</term><term>Iterative changes</term><term>Leroy</term><term>Lichen sclerosis</term><term>Limited cutaneous</term><term>Lung disease</term><term>Maximum score</term><term>Medical university</term><term>Medsger</term><term>Metacarpophalangeal</term><term>Metacarpophalangeal joints</term><term>Multicriteria decision analysis</term><term>Nailfold</term><term>Nailfold capillaries</term><term>Nailfold capillaroscopy</term><term>Nailfold capillary pattern</term><term>Nailfold visualisation</term><term>Ngers</term><term>Ngertip lesions</term><term>Patient data</term><term>Physician diagnosis</term><term>Point system</term><term>Preliminary criteria</term><term>Present work</term><term>Prospective study</term><term>Proximal</term><term>Proximal interphalangeal</term><term>Pulmonary artery hypertension</term><term>Radboud university nijmegen</term><term>Random sample</term><term>Renal crisis</term><term>Research grants</term><term>Rheum</term><term>Rheumatic disease</term><term>Rheumatic diseases</term><term>Rheumatism</term><term>Rheumatism criteria</term><term>Rheumatoid arthritis</term><term>Rheumatol</term><term>Rheumatology</term><term>Scleredema diabeticorum</term><term>Scleroderma</term><term>Scleroderma criteria</term><term>Sclerosis</term><term>Systemic</term><term>Systemic lupus erythematosus</term><term>Systemic sclerosis</term><term>Systemic sclerosis criteria</term><term>Telangiectasia</term><term>Tissue disease</term><term>Total score</term><term>Validation</term><term>Validation cohort</term><term>Validation sample</term><term>Weighted</term><term>Whole finger</term><term>Years time</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract">Objective The 1980 American College of Rheumatology (ACR) classification criteria for systemic sclerosis (SSc) lack sensitivity for early SSc and limited cutaneous SSc. The present work, by a joint committee of the ACR and the European League Against Rheumatism (EULAR), was undertaken for the purpose of developing new classification criteria for SSc. Methods Using consensus methods, 23 candidate items were arranged in a multicriteria additive point system with a threshold to classify cases as SSc. The classification system was reduced by clustering items and simplifying weights. The system was tested by (1) determining specificity and sensitivity in SSc cases and controls with scleroderma-like disorders, and (2) validating against the combined view of a group of experts on a set of cases with or without SSc. Results It was determined that skin thickening of the fingers extending proximal to the metacarpophalangeal joints is sufficient for the patient to be classified as having SSc; if that is not present, seven additive items apply, with varying weights for each: skin thickening of the fingers, fingertip lesions, telangiectasia, abnormal nailfold capillaries, interstitial lung disease or pulmonary arterial hypertension, Raynaud's phenomenon, and SSc-related autoantibodies. Sensitivity and specificity in the validation sample were, respectively, 0.91 and 0.92 for the new classification criteria and 0.75 and 0.72 for the 1980 ACR classification criteria. All selected cases were classified in accordance with consensus-based expert opinion. All cases classified as SSc according to the 1980 ACR criteria were classified as SSc with the new criteria, and several additional cases were now considered to be SSc. Conclusions The ACR/EULAR classification criteria for SSc performed better than the 1980 ACR criteria for SSc and should allow for more patients to be classified correctly as having the disease.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Canada</li><li>Espagne</li><li>France</li><li>Hongrie</li><li>Irlande (pays)</li><li>Italie</li><li>Nouvelle-Zélande</li><li>Pays-Bas</li><li>Pologne</li><li>Royaume-Uni</li><li>Suisse</li><li>Turquie</li><li>États-Unis</li></country><region><li>Angleterre</li><li>Berlin</li><li>Californie</li><li>Caroline du Sud</li><li>Colorado</li><li>Communauté de Madrid</li><li>Connecticut</li><li>District de Columbia</li><li>Grand Londres</li><li>Grand Manchester</li><li>Gueldre</li><li>Illinois</li><li>Massachusetts</li><li>Michigan</li><li>Midlands de l'Ouest</li><li>New Jersey</li><li>Ohio</li><li>Ontario</li><li>Pennsylvanie</li><li>Texas</li><li>Île-de-France</li></region><settlement><li>Berlin</li><li>Birmingham</li><li>Londres</li><li>Los Angeles</li><li>Madrid</li><li>Manchester</li><li>Nimègue</li><li>Paris</li><li>Toronto</li></settlement><orgName><li>Université de Manchester</li><li>Université de Toronto</li></orgName></list><tree><country name="Pays-Bas"><region name="Gueldre"><name sortKey="Van Den Hoogen, Frank" sort="Van Den Hoogen, Frank" uniqKey="Van Den Hoogen F" first="Frank" last="Van Den Hoogen">Frank Van Den Hoogen</name></region><name sortKey="Fransen, Jaap" sort="Fransen, Jaap" uniqKey="Fransen J" first="Jaap" last="Fransen">Jaap Fransen</name><name sortKey="Vonk, Madelon C" sort="Vonk, Madelon C" uniqKey="Vonk M" first="Madelon C" last="Vonk">Madelon C. Vonk</name></country><country name="États-Unis"><region name="Michigan"><name sortKey="Khanna, Dinesh" sort="Khanna, Dinesh" uniqKey="Khanna D" first="Dinesh" last="Khanna">Dinesh Khanna</name></region><name sortKey="Chung, Lorinda" sort="Chung, Lorinda" uniqKey="Chung L" first="Lorinda" last="Chung">Lorinda Chung</name><name sortKey="Clements, Philip J" sort="Clements, Philip J" uniqKey="Clements P" first="Philip J" last="Clements">Philip J. Clements</name><name sortKey="Collier, David H" sort="Collier, David H" uniqKey="Collier D" first="David H" last="Collier">David H. Collier</name><name sortKey="Collier, David H" sort="Collier, David H" uniqKey="Collier D" first="David H" last="Collier">David H. Collier</name><name sortKey="Ellen Csuka, Mary" sort="Ellen Csuka, Mary" uniqKey="Ellen Csuka M" first="Mary" last="Ellen Csuka">Mary Ellen Csuka</name><name sortKey="Furst, Daniel E" sort="Furst, Daniel E" uniqKey="Furst D" first="Daniel E" last="Furst">Daniel E. Furst</name><name sortKey="Hsu, Vivien M" sort="Hsu, Vivien M" uniqKey="Hsu V" first="Vivien M" last="Hsu">Vivien M. Hsu</name><name sortKey="Jimenez, Sergio" sort="Jimenez, Sergio" uniqKey="Jimenez S" first="Sergio" last="Jimenez">Sergio Jimenez</name><name sortKey="Kahaleh, Bashar" sort="Kahaleh, Bashar" uniqKey="Kahaleh B" first="Bashar" last="Kahaleh">Bashar Kahaleh</name><name sortKey="Mayes, Maureen D" sort="Mayes, Maureen D" uniqKey="Mayes M" first="Maureen D" last="Mayes">Maureen D. Mayes</name><name sortKey="Medsger, Thomas A" sort="Medsger, Thomas A" uniqKey="Medsger T" first="Thomas A" last="Medsger">Thomas A. Medsger</name><name sortKey="Merkel, Peter A" sort="Merkel, Peter A" uniqKey="Merkel P" first="Peter A" last="Merkel">Peter A. Merkel</name><name sortKey="Merkel, Peter A" sort="Merkel, Peter A" uniqKey="Merkel P" first="Peter A" last="Merkel">Peter A. Merkel</name><name sortKey="Seibold, James R" sort="Seibold, James R" uniqKey="Seibold J" first="James R" last="Seibold">James R. Seibold</name><name sortKey="Silver, Richard M" sort="Silver, Richard M" uniqKey="Silver R" first="Richard M" last="Silver">Richard M. Silver</name><name sortKey="Simms, Robert W" sort="Simms, Robert W" uniqKey="Simms R" first="Robert W" last="Simms">Robert W. Simms</name><name sortKey="Steen, Virginia D" sort="Steen, Virginia D" uniqKey="Steen V" first="Virginia D" last="Steen">Virginia D. Steen</name><name sortKey="Varga, John" sort="Varga, John" uniqKey="Varga J" first="John" last="Varga">John Varga</name></country><country name="Canada"><region name="Ontario"><name sortKey="Johnson, Sindhu R" sort="Johnson, Sindhu R" uniqKey="Johnson S" first="Sindhu R" last="Johnson">Sindhu R. Johnson</name></region><name sortKey="Baron, Murray" sort="Baron, Murray" uniqKey="Baron M" first="Murray" last="Baron">Murray Baron</name><name sortKey="Pope, Janet E" sort="Pope, Janet E" uniqKey="Pope J" first="Janet E" last="Pope">Janet E. Pope</name></country><country name="Suisse"><noRegion><name sortKey="Tyndall, Alan" sort="Tyndall, Alan" uniqKey="Tyndall A" first="Alan" last="Tyndall">Alan Tyndall</name></noRegion><name sortKey="Distler, Oliver" sort="Distler, Oliver" uniqKey="Distler O" first="Oliver" last="Distler">Oliver Distler</name><name sortKey="Walker, Ulrich A" sort="Walker, Ulrich A" uniqKey="Walker U" first="Ulrich A" last="Walker">Ulrich A. Walker</name></country><country name="Italie"><noRegion><name sortKey="Matucci Cerinic, Marco" sort="Matucci Cerinic, Marco" uniqKey="Matucci Cerinic M" first="Marco" last="Matucci-Cerinic">Marco Matucci-Cerinic</name></noRegion><name sortKey="Gabrielli, Armando" sort="Gabrielli, Armando" uniqKey="Gabrielli A" first="Armando" last="Gabrielli">Armando Gabrielli</name><name sortKey="Guiducci, Serena" sort="Guiducci, Serena" uniqKey="Guiducci S" first="Serena" last="Guiducci">Serena Guiducci</name><name sortKey="Valentini, Gabriele" sort="Valentini, Gabriele" uniqKey="Valentini G" first="Gabriele" last="Valentini">Gabriele Valentini</name></country><country name="Nouvelle-Zélande"><noRegion><name sortKey="Naden, Raymond P" sort="Naden, Raymond P" uniqKey="Naden R" first="Raymond P" last="Naden">Raymond P. Naden</name></noRegion></country><country name="Espagne"><region name="Communauté de Madrid"><name sortKey="Carreira, Patricia E" sort="Carreira, Patricia E" uniqKey="Carreira P" first="Patricia E" last="Carreira">Patricia E. Carreira</name></region></country><country name="Allemagne"><region name="Berlin"><name sortKey="Riemekasten, Gabriela" sort="Riemekasten, Gabriela" uniqKey="Riemekasten G" first="Gabriela" last="Riemekasten">Gabriela Riemekasten</name></region><name sortKey="Muller Ladner, Ulf" sort="Muller Ladner, Ulf" uniqKey="Muller Ladner U" first="Ulf" last="Müller-Ladner">Ulf Müller-Ladner</name></country><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Denton, Christopher P" sort="Denton, Christopher P" uniqKey="Denton C" first="Christopher P" last="Denton">Christopher P. Denton</name></region><name sortKey="Fessler, Barri J" sort="Fessler, Barri J" uniqKey="Fessler B" first="Barri J" last="Fessler">Barri J. Fessler</name><name sortKey="Herrick, Ariane" sort="Herrick, Ariane" uniqKey="Herrick A" first="Ariane" last="Herrick">Ariane Herrick</name><name sortKey="Herrick, Ariane" sort="Herrick, Ariane" uniqKey="Herrick A" first="Ariane" last="Herrick">Ariane Herrick</name><name sortKey="Van Laar, Jacob M" sort="Van Laar, Jacob M" uniqKey="Van Laar J" first="Jacob M" last="Van Laar">Jacob M. Van Laar</name></country><country name="France"><region name="Île-de-France"><name sortKey="Allanore, Yannick" sort="Allanore, Yannick" uniqKey="Allanore Y" first="Yannick" last="Allanore">Yannick Allanore</name></region></country><country name="Hongrie"><noRegion><name sortKey="Czirjak, Laszlo" sort="Czirjak, Laszlo" uniqKey="Czirjak L" first="Laszlo" last="Czirjak">Laszlo Czirjak</name></noRegion></country><country name="Turquie"><noRegion><name sortKey="Inanc, Murat" sort="Inanc, Murat" uniqKey="Inanc M" first="Murat" last="Inanc">Murat Inanc</name></noRegion></country><country name="Pologne"><noRegion><name sortKey="Kowal Bielecka, Otylia" sort="Kowal Bielecka, Otylia" uniqKey="Kowal Bielecka O" first="Otylia" last="Kowal-Bielecka">Otylia Kowal-Bielecka</name></noRegion><name sortKey="Sierakowski, Stanislav" sort="Sierakowski, Stanislav" uniqKey="Sierakowski S" first="Stanislav" last="Sierakowski">Stanislav Sierakowski</name></country><country name="Irlande (pays)"><noRegion><name sortKey="Veale, Douglas J" sort="Veale, Douglas J" uniqKey="Veale D" first="Douglas J" last="Veale">Douglas J. Veale</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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